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The non-enzymatic succinylation is mainly mediated by intracellular succinyl-CoA which can be modulated by succinyl-CoA metabolism-targeting enzymes, such as OXCT1, a member of the CoA transferase family I [49], and SUCLA2/SUCLG2, the ADP-forming succinyl-CoA synthetase [32, 50]

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Sweet proteins lysozyme and thaumatin are protein-type agonists for the calcium-sensing receptor