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Semaglutide has recently been reported to promote NASH resolution (Newsome et al., NEJM, 2020) and is currently in phase 3 clinical trial (ESSENCE) for NASH

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It was not due to a lack of nitrobenzene transfer across red blood cell membranes, because [ 14 C]nitrobenzene accumulated to the same extent as labelled o - and p -dinitrobenzenes, compounds that cause methaemoglobin formation after being metabolized by glutathione transferase (Rickert, 1987)