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However, MGST1 was observed to decrease in middle- and old-age rat liver compared to young rats, consistent with the upregulation of miR-34a and miR-93 during aging and downregulation of their targets SP1 and Nrf2 which are the transcription factors for MGST1 (Li, Muthusamy, Liang, Sarojini, & Wang, 2011)

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Changes in blood pressure and heart rate were recorded at four time points: upon entering the operating room (T1), immediately after tracheal intubation (T2), immediately after incision (T3), and immediately after surgery completion (T4)