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There are data, but no direct proof as of yet, associating T cell NF-κB signaling with the risk and maintenance of MS

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These molecular interactions – as shown in Figure 4 – occur across the airway epithelial cell, airway smooth muscle cell, endothelial cell, pericyte, fibroblast, central and peripheral neurons innervate the airways, and lung resident immune cells such as dendritic cell, microglia, macrophage, CD4+ T cell, Th1 cell, Th2 cell, Th17 cell, Treg cell, B cell, mast cell, ILC2 cell, CD8+ T cell, neutrophil and eosinophil