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Free Radical Biology and Medicine, 2018
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The Bowers and colleagues canonical work across the 1980s and 1990s reported synergistic growth hormone release at the somatotroph when a GHRH analog and a GHRP-class agent were co-administered, with the synergy mechanism interpreted as pulse-amplitude (GHRH-R) versus basal-frequency (GHS-R1a) control of pituitary growth hormone release [5]
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