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NNMT inhibitor caused weight loss and reduced adipose tissue mass in DIO mice Since in vitro studies showed 5-amino-1MQ to have high cell permeability, enzyme selectivity, and cell culture efficacy, a sub-chronic (11-day) proof-of-concept in vivo study was conducted to test the effect of NNMT inhibition on obesity in HFD fed mice

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Eye benefits of lutein and zeaxanthin It is believed that lutein, zeaxanthin and meso-zeaxanthin in the macula filter light from reaching the underlying structures in the retina, thereby reducing the risk of light-induced oxidative damage that could lead to macular degeneration (AMD)