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Additionally, neonatal mice colonized with Staphylococcus exhibit strong Th17 polarization, leading to increased production of IL-17A and exacerbation of skin lesions ( Staphylococcus is not simply a result of structural changes in the skin caused by psoriasis, but rather an important trigger for disease progression

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For expression into mammalian cell mitochondria, the pCDNA3.1 Cystector (HindIII digested) was C-terminally fused to a 2xCOXVIII mitochondrial targetting presequence via HiFi DNA assembly