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Its core pathological features include the progressive loss of dopaminergic neurons in the substantia nigra pars compacta and the formation of Lewy bodies, which results from the abnormal aggregation of α-syn ( 2 Materials and methods 2.1 Data sources 2.1.1 Search execution The initial literature search was conducted by the first author in October 2025

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doi: 10.1155/2016/3286365 32