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Antiaggregant Activity towards Aβ One of the main factors involved in the onset and/or progression of neurodegenerative disorders is the abnormal accumulation of intrinsically disordered proteins, whose natural folding state is somehow modified, and they become more prone to forming soluble and toxic oligomers first

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Two robust regression LME models (package(nlme)(Pinheiro et al., 2023)) were estimated for each brain region to investigate the relationship between metabolite (GSH or GABA+) levels and diagnosis group, age, and sex, accounting for the random intercept of each participant

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